Brief description of the research
The subject of Dr. Igor Saveljić's research is the field of computational fluid dynamics and numerical simulations. The emphasis is on the study of blood flow through blood vessels and the problems that arise in this process, as well as on determining the causes that lead to the process of atherosclerosis in the coronary and carotid arteries and the methods of its further development using computer numerical simulations. The starting point is real DICOM images obtained from the world's leading clinical centers. By applying modern software solutions, they are reconstructed into 3D models that serve as an input for further three-dimensional solving of blood flow problems.
Selected references
- Nenad Filipovic, Dalibor Nikolic, Igor Saveljic, Zarko Milosevic, Themis Exarchos, Gualtiero Pelosi, Oberdan Parodi, Computer simulation of three dimensional plaque formation and progression in the coronary artery, Computers and Fluids, 88, 826–833, 2013. http://dx.doi.org/10.1016/j.compfluid.2013.07.006
- Brönnimann D, Djukic T, Triet R, Dellenbach C, Saveljic I, Rieger M, Rohr S, Filipovic N, Djonov V, Pharmacological Modulation of Hemodynamics in Adult Zebrafish In Vivo, PLoS ONE, 11(3): e0150948, 2016. https://doi.org/10.1371/journal.pone.0150948
- Tijana Djukic, Igor Saveljic, Gualtiero Pelosi, Oberdan Parodi, Nenad Filipovic, Numerical simulation of stent deployment within patient-specific artery and its validation against clinical data, Computer Methods and Programs in Biomedicine, 175, 121–127, 2019. https://doi.org/10.1016/j.cmpb.2019.04.005
- Filipovic N., Saveljic I., Hamada K. et al., Abrupt Deterioration of COVID-19 Patients and Spreading of SARS COV-2 Virions in the Lungs, Annals of Biomedical Engineering, 48, 2705–2706, 2020. https://doi.org/10.1007/s10439-020-02676-w
- Tijana Djukic, Igor Saveljic, Gualtiero Pelosi, Oberdan Parodi, Nenad Filipovic, A study on the accuracy and efficiency of the improved numerical model for stent implantation using clinical data, Computer Methods and Programs in Biomedicine, 207, 106196, 2021. https://doi.org/10.1016/j.cmpb.2021.106196