{"id":21099,"date":"2025-11-14T10:16:46","date_gmt":"2025-11-14T10:16:46","guid":{"rendered":"https:\/\/iit.ac.rs\/?page_id=21099"},"modified":"2026-03-04T09:30:01","modified_gmt":"2026-03-04T09:30:01","slug":"dr-emina-mrkalic","status":"publish","type":"page","link":"https:\/\/iit.ac.rs\/en\/dr-emina-mrkalic\/","title":{"rendered":"Dr Emina Mrkali\u0107"},"content":{"rendered":"
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\r\n \"\u0434\u0440\r\n <\/div>\r\n\r\n \r\n
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Dr Emina Mrkali\u0107<\/h2>\r\n\r\n
\r\n Senior research\nassociate<\/span>\r\n Bioorganic and bioinorganic chemistry<\/span>\r\n <\/div>\r\n\r\n
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Education:<\/b> Doctor of Science - Chemical Sciences<\/div>\r\n
Address:<\/b> Institute of Information Technology Kragujevac, Jovana Cviji\u0107a bb, 34000 Kragujevac.<\/div>\r\n
Email:<\/b> emina.mrkalic@pmf.kg.ac.rs<\/div>\r\n
IBI (Researcher Identification Number):<\/b> AN032<\/div>\r\n <\/div>\r\n\r\n \r\n
\r\n\r\n \r\n \"eNauka\"\r\n <\/a>\r\n\r\n \r\n \"SCIDAR\"\r\n <\/a>\r\n\r\n \r\n \"ORCID\"\r\n <\/a>\r\n\r\n \r\n \"ResearchGate\"\r\n <\/a>\r\n\r\n \r\n \"Scopus\"\r\n <\/a>\r\n\r\n <\/div>\r\n\r\n \r\n
\r\n\r\n \r\n \ud83d\udcc4<\/span> CV - Serbian\r\n <\/a>\r\n\r\n \r\n \ud83d\udcc4<\/span> CV \u2013 English\r\n <\/a>\r\n\r\n <\/div>\r\n\r\n <\/div>\r\n\r\n \r\n
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\r\n Brief description of the research<\/summary>\r\n\r\n
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\r\n Research includes:\r\n <\/p>\r\n\r\n

\r\n \u0430)<\/b> Determining structural changes during the binding of commercial drugs to certain blood plasma proteins, as well as examining the specificity of drug-protein interactions in simulated physiological conditions.\r\n <\/p>\r\n\r\n

\r\n \u0431)<\/b> Testing the interactions of newly synthesized compounds with human serum proteins and a DNA molecule (calf DNA). Binding constants, binding sites, thermodynamic parameters and the nature of the forces involved in binding are determined.\r\n <\/p>\r\n \r\n

In this way, binding constants will be determined, as well as binding sites, thermodynamic parameters, and the nature of binding forces between the drug\/newly synthesized compounds and proteins.<\/p>\r\n <\/div>\r\n\r\n <\/details>\r\n\r\n \r\n

\r\n Selected references<\/summary>\r\n\r\n
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  1. \r\n Emina M. Mrkali\u0107, Ratomir M. Jeli\u0107, Olivera R. Klisuri\u0107, Zoran D. Matovi\u0107,\r\n Synthesis of novel palladium(II) complexes with oxalic acid diamide derivatives and their interaction with nucleosides and proteins<\/i>,\r\n Dalton Transactions, 43 (2014) 15126\u201315137.\r\n https:\/\/doi.org\/10.1039\/C3DT53384K.\r\n <\/li>\r\n\r\n
  2. \r\n Emina Mrkali\u0107, Ratomir Jeli\u0107, Stefan Stojanovi\u0107, Miroslav Sovrli\u0107,\r\n Interaction between olanzapine and human serum albumin and effect of metal ions, caffeine and flavonoids on the binding: A spectroscopic study<\/i>,\r\n Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 249 (2021) 119295.\r\n https:\/\/doi.org\/10.1016\/j.saa.2020.119295.\r\n <\/li>\r\n\r\n
  3. \r\n Miroslav Sovrli\u0107, Emina Mrkali\u0107, Ratomir Jeli\u0107, Marina \u0106endi\u0107 Serafinovi\u0107, Stefan Stojanovi\u0107, Nevena Prodanovi\u0107, Jovica Tomovi\u0107,\r\n Effect of caffeine and flavonoids on the binding of tigecycline to human serum albumin: A spectroscopic study and molecular docking<\/i>,\r\n Pharmaceuticals, 15(3) (2022) 266.\r\n https:\/\/doi.org\/10.3390\/ph15030266.\r\n <\/li>\r\n\r\n <\/ol>\r\n <\/div>\r\n\r\n <\/details>\r\n\r\n <\/div>\r\n <\/div>\r\n\r\n<\/div>\r\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

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