{"id":21152,"date":"2025-11-17T09:05:25","date_gmt":"2025-11-17T09:05:25","guid":{"rendered":"https:\/\/iit.ac.rs\/?page_id=21152"},"modified":"2026-03-04T10:58:50","modified_gmt":"2026-03-04T10:58:50","slug":"dr-%d1%98elena-kosaric","status":"publish","type":"page","link":"https:\/\/iit.ac.rs\/en\/dr-%d1%98elena-kosaric\/","title":{"rendered":"Dr Jelena Ko\u0161ari\u0107"},"content":{"rendered":"
\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\r\n\r\n \r\n
\r\n \"\u0434\u0440\r\n <\/div>\r\n\r\n \r\n
\r\n

Dr Jelena Ko\u0161ari\u0107<\/h2>\r\n\r\n
\r\n Research associate<\/span>\r\n Bioinformatics and applied biology<\/span>\r\n <\/div>\r\n\r\n
\r\n
Education:<\/b> Doctor of Science - Biological Sciences \/ Specialist in Organic Chemistry<\/div>\r\n
Address:<\/b> Institute of Information Technologies Kragujevac, Liceja Kne\u017eevine Srbije 1A, 34000 Kragujevac.<\/div>\r\n
Email:<\/b> jelena.kosaric@uni.kg.ac.rs<\/div>\r\n <\/div>\r\n\r\n \r\n
\r\n\r\n \r\n \"eNauka\"\r\n <\/a>\r\n\r\n \r\n \"SCIDAR\"\r\n <\/a>\r\n\r\n \r\n \"ORCID\"\r\n <\/a>\r\n\r\n \r\n \"ResearchGate\"\r\n <\/a>\r\n\r\n \r\n \"LinkedIn\"\r\n <\/a>\r\n\r\n \r\n \"Scopus\"\r\n <\/a>\r\n\r\n <\/div>\r\n\r\n \r\n
\r\n\r\n \r\n \ud83d\udcc4<\/span> CV - Serbian\r\n <\/a>\r\n\r\n \r\n \ud83d\udcc4<\/span> CV \u2013 English\r\n <\/a>\r\n\r\n <\/div>\r\n\r\n <\/div>\r\n\r\n \r\n
\r\n
\r\n\r\n \r\n
\r\n Brief description of the research<\/summary>\r\n\r\n
\r\n\r\n

\r\n Investigation of the molecular mechanisms of the influence of organoselen compounds (OSCs) on the redox status of immortalized HCT-116 colon carcinoma and MDA-MB-231 breast carcinoma cell lines.\r\n <\/p>\r\n\r\n

\r\n Examination of the effects of OSJ on the migratory potential of HCT-116 and MDA-MB-231 cells using the Transwell migration assay.\r\n <\/p>\r\n\r\n

\r\n Determination of the influence of OSJ on the expression of mRNA target genes for seleno-enzymes in HCT-116 cells by quantitative PCR.\r\n <\/p>\r\n\r\n

\r\n Examination of the effects of OSJ on the activity of the transcription factors Nrf2, HIF and NF-\u03baB, as well as their interrelationships, using fluorescent methodology, transfection of the pTRAF vector and analysis on the Operetta system at single-cell resolution.\r\n <\/p>\r\n\r\n <\/div>\r\n\r\n <\/details>\r\n\r\n \r\n

\r\n Selected references<\/summary>\r\n\r\n
\r\n\r\n
    \r\n\r\n
  1. \r\n \u017divanovi\u0107 MN, Ko\u0161ari\u0107 JV, \u0160mit BM, \u0160ekli\u0107 DS, Pavlovi\u0107 RZ, Markovi\u0107 SD. \r\n Novel seleno-hydantoin palladium (II) complex \u2013 antimigratory, cytotoxic and prooxidative potential on human colon HCT-116 and breast MDA-MB-231 cancer cells<\/i>. \r\n General Physiology and Biophysics, 2017, 36(2): 187\u2013196.\r\n <\/li>\r\n\r\n
  2. \r\n \u010canovi\u0107 PP, Bogojevski JV, Ko\u0161ari\u0107 JV, Markovi\u0107 SD, \u017divanovi\u0107 MN. \r\n Pt (IV), Pd (II), and Rh (III) complexes induced oxidative stress and cytotoxicity in the HCT-116 colon cancer cell line<\/i>. \r\n Turkish Journal of Biology, 2017, 41(1): 141\u2013147.\r\n <\/li>\r\n\r\n
  3. \r\n Ko\u0161ari\u0107 JV, Cvetkovi\u0107 DM, \u017divanovi\u0107 MN, \u0106ur\u010di\u0107 MG, \u0160ekli\u0107 DS, Bugar\u010di\u0107 ZM, Markovi\u0107 SD. \r\n Antioxidative and antiproliferative evaluation of 2-(phenylselenomethyl)tetrahydrofuran and 2-(phenylselenomethyl)tetrahydropyran<\/i>. \r\n J BOUN, 2014, 19(1): 283\u2013290.\r\n <\/li>\r\n\r\n
  4. \r\n Petrovi\u0107 VP, Simijonovi\u0107 D, \u017divanovi\u0107 MN, Ko\u0161ari\u0107 JV, Petrovi\u0107 ZD, Markovi\u0107 S, Markovi\u0107 SD. \r\n Vanillic Mannich bases: synthesis and screening of biological activity...<\/i> \r\n RSC Advances, 2014, 4(47): 24635\u201324644.\r\n <\/li>\r\n\r\n
  5. \r\n \u017divanovi\u0107 MN, Cvetkovi\u0107 DM, Ko\u0161ari\u0107 JV, \u0106ur\u010di\u0107 MG, \u0160ekli\u0107 DS, Bugar\u010di\u0107 ZM, Markovi\u0107 SD. \r\n Antioxidative effects of novel selenium compounds<\/i>. \r\n FEBS Journal, 2012, 279(1): 197\u2013197.\r\n <\/li>\r\n\r\n <\/ol>\r\n\r\n <\/div>\r\n\r\n <\/details>\r\n\r\n <\/div>\r\n <\/div>\r\n\r\n<\/div>\r\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    \u0434\u0440 \u0408\u0435\u043b\u0435\u043d\u0430 \u041a\u043e\u0448\u0430\u0440\u0438\u045b \u041d\u0430\u0443\u0447\u043d\u0438 \u0441\u0430\u0440\u0430\u0434\u043d\u0438\u043a \u0411\u0438\u043e\u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u043a\u0430 \u0438 \u043f\u0440\u0438\u043c\u0435\u045a\u0435\u043d\u0430 \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0458\u0430 \u041e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u045a\u0435: \u0414\u043e\u043a\u0442\u043e\u0440 \u043d\u0430\u0443\u043a\u0430 \u2013 \u0431\u0438\u043e\u043b\u043e\u0448\u043a\u0435 \u043d\u0430\u0443\u043a\u0435 \/ \u0421\u043f\u0435\u0446\u0438\u0458\u0430\u043b\u0438\u0441\u0442\u0430 \u043e\u0440\u0433\u0430\u043d\u0441\u043a\u0435 \u0445\u0435\u043c\u0438\u0458\u0435 \u0410\u0434\u0440\u0435\u0441\u0430: \u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0437\u0430 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u043e\u043d\u0435 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0458\u0435 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0430\u0446, \u041b\u0438\u0446\u0435\u0458\u0430 \u041a\u043d\u0435\u0436\u0435\u0432\u0438\u043d\u0435 \u0421\u0440\u0431\u0438\u0458\u0435 1\u0410, 34000 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0430\u0446. \u0415-\u043f\u043e\u0448\u0442\u0430: jelena.kosaric@uni.kg.ac.rs \ud83d\udcc4 CV \u2013 \u0421\u0440\u043f\u0441\u043a\u0438 \ud83d\udcc4 CV \u2013 English \u041a\u0440\u0430\u0442\u0430\u043a \u043e\u043f\u0438\u0441 \u0438\u0441\u0442\u0440\u0430\u0436\u0438\u0432\u0430\u045a\u0430 \u0418\u0441\u043f\u0438\u0442\u0438\u0432\u0430\u045a\u0435 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u0430\u0440\u043d\u0438\u0445 \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u0430\u043c\u0430 \u0443\u0442\u0438\u0446\u0430\u0458\u0430 \u043e\u0440\u0433\u0430\u043d\u043e\u0441\u0435\u043b\u0435\u043d\u0441\u043a\u0438\u0445 \u0458\u0435\u0434\u0438\u045a\u0435\u045a\u0430 (\u041e\u0421\u0408) \u043d\u0430 \u0440\u0435\u0434\u043e\u043a\u0441 \u0441\u0442\u0430\u0442\u0443\u0441 \u0438\u043c\u043e\u0440\u0442\u0430\u043b\u0438\u0437\u043e\u0432\u0430\u043d\u0438\u0445…<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-21152","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/pages\/21152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/comments?post=21152"}],"version-history":[{"count":4,"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/pages\/21152\/revisions"}],"predecessor-version":[{"id":21158,"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/pages\/21152\/revisions\/21158"}],"wp:attachment":[{"href":"https:\/\/iit.ac.rs\/en\/wp-json\/wp\/v2\/media?parent=21152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}