Dr Dragana Šeklić
Senior research
associate
Bioinformatics and applied biology
Brief description of the research
The focus of Dr. Dragana Šeklić's research is on studying the anticancer effect of newly synthesized chemical complexes and bioactive substances from natural sources. In particular, the focus is on the molecular mechanisms of migration and invasion, as well as key signaling pathway proteins involved in these processes. A significant part of the research also includes coculture systems, i.e. interactions between microorganisms and colorectal cancer cells , with the aim of better understanding the influence of the microenvironment on tumor progression.
Selected references
- Nikolić S, Gazdić-Janković M, Rosić G, Miletić-Kovacević M, Jovičić N, Nestorović N, Stojkovic P, Filipovic N, Milosevic-Djordjevic O, Selakovic D, Zivanovic M, Seklic D, Milivojević N, Markovic A, Seist R, Vasilijic S, Stankovic K, Stojkovic M, Ljujic B, Orally administered fluorescent nanosized polystyrene particles affect cell viability, hormonal and inflammatory profile, and behavior in treated mice, Environmental Pollution, 2022, 305, 119206. https://doi.org/10.1016/j.envpol.2022.11920
- Šeklić D, Đukić T, Milenković D, Jovanović M, Živanović M, Marković Z, Filipović N, Numerical modelling of WNT/β-catenin signal pathway in characterization of EMT of colorectal carcinoma cell lines after treatment with Pt(IV) complexes, Computer Methods and Programs in Biomedicine, 2022, 221, 107158. https://doi.org/10.1016/j.cmpb.2022.107158
- Šeklić D, Jovanović M, Virijević K, Grujić J, Živanović M, Marković S, Pseudevernia furfuracea inhibits migration and invasion of colorectal carcinoma cell lines, Journal of Ethnopharmacology, 2022, 284, 114758. https://doi.org/10.1016/j.jep.2021.114758
- Jovanović M, Šeklić D, Rakobradović J, Planojević N, Vuković N, Vukić M, Marković S, Royal jelly and Trans-10-Hydroxy-2-Decenoic Acid Inhibit Migration and Invasion of Colorectal Carcinoma Cells, Food Technology and Biotechnology, 2022, 60(2), 213–224. https://doi.org/10.17113/ftb.60.02.22.7495
- Kosanić M, Šeklić D, Jovanović M, Petrović N, Marković S, Hygrophorus eburneus, edible mushroom, a promising natural bioactive agent, EXCLI Journal, 2020, 19, 442–457.