Katarina Virijević
Research assistant
Master of Science in Chemistry - Environmental Protection / Master of Science in Biomedical Engineeringv
Bioinformatics and applied biology
Brief description of the research
Katarina Virijević's research focuses on the synthesis and characterization of biologically active derivatives of 2-thiohydantoin, as well as on the investigation of their various biological activities.
The experimental part includes the synthesis and analysis of several series of molecular hybrids of 2-thiohydantoin, including spectral and crystallographic data, as well as biological, theoretical and spectroscopic investigations.
The interaction of newly synthesized compounds with DNA, BSA and HSA proteins is also investigated. Binding to DNA is analyzed by UV-Vis and fluorescence spectroscopy, based on which binding constants and mechanisms are determined.
Selected references
- Virijević K. D., Stanić P., Muškinja J. M., Katanić Stanković J., ... Synthesis and biological activity of novel zingerone-thiohydantoin hybrids, Journal of the Serbian Chemical Society (2022). DOI: 10.2298/JSC220404047V
- Petrović A. Z., Ćoćić D. C., Bockfeld D., Živanović M., Virijević K., et al., Biological activity of Os(II) complexes in the presence of ionic liquids, Inorganic Chemistry Frontiers 8 (2021) 2749–2770. DOI: 1039/D0QI01540G
- Šeklić D. Š., Jovanović M. M., Virijević K. D., ... Pseudevernia furfuracea inhibits migration and invasion..., Journal of Ethnopharmacology 284 (2022) 114758. DOI: 10.1016/j.jep.2021.114758