Brief description of the research
The researcher is actively engaged in scientific research in the field of genetics, with a focus on the integrative application of biotechnological methods in the study of genomic instability in peripheral blood lymphocytes of patients with endometrial carcinoma.
It is particularly focused on examining the genotoxic and antimutagenic effects of various substances on the genetic material of healthy cells. The results so far provide a significant contribution to the assessment of the safety of application and potential therapeutic effect of substances of natural origin.
Selected references
- Marković A., Grujičić D., Živković Radojević M., Milošević-Djordjević O. Measurement of chromosomal instability and level of DNA damage in peripheral blood mononuclear cells of endometrial cancer patients. Mutagenesis, 2024. IF2022 = 2.7; ISSN 0267-8357; doi: 10.1093/mutage/geae003 (M22).
- Marković A., Tubić Vukajlović J., Grujičić D., Radović Jakovljević M., Stanković M., Djordjević K., Djelić N., Radaković M., Milošević-Djordjević O. Methanol extracts of Teucrium arduini L. and Teucrium flavum L. induce protective effect against mitomycin C in human lymphocytes in vitro. Drug and Chemical Toxicology, 2022, 45(1), 940–946. IF2022 = 2.6; ISSN 0148-0545; DOI: 10.1080/01480545.2020.1802477 (M23).
- Nikolic S., Gazdic-Jankovic M., Rosic G., Miletic-Kovacevic M., Jovicic N., Nestorovic N., Stojkovic P., Filipovic N., Milosevic-Djordjevic O., Selakovic D., Živanovic M., Seklic D., Milivojević N., Markovic A., Seistij R., Vasilijici S., Stankovic K.M., Stojkovic M., Ljujic B. Orally administered fluorescent nanosized polystyrene particles affect cell viability, hormonal and inflammatory profile, and behavior in treated mice. Environmental Pollution, 2022, 305, 119206. IF2022 = 8.9; ISSN 0269-7491; DOI: 10.1016/j.envpol.2022.119206 (M21).
- Mihaljevic O., Zivancevic-Simonovic S., Jovanovic D., Miletic Drakulic S., Tubic Vukajlovic J., Markovic A., Stanojevic Pirkovic M., Srejovic I., Jakovljevic V., Milosevic-Djordjevic O. Oxidative stress and DNA damage in critically ill patients with sepsis. Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 2023, 889, 503655. IF2022 = 1.9; ISSN 1383-5718; DOI: 10.1016/j.mrgentox.2023.503655 (M22).